Differences such as this may be attributed to, the chronological age of the plant, percentage humidity of the harvested material, situation and time of harvest, and whether the method of extraction was a possible source of variation for the chemical composition, toxicity and bioactivity of the extracts Felix, Sign In Join Now. Structured questionnaires were used to explore the ethnobotanical practices amongst the traditional healers. Herbal medicinal is neglected because it lack scientific analysis and most plant have physiological effect on human but its chemical and organic constituent are not determined. J Med Food Apr;13 2: J Ethnopharmacol Jul 20; Thus targeting HDACs with inhibitors is a major focus in anticancer drug research.
Some phytochemicals act as preventive and or scavenging antioxidants. All treatments lasted 14 days after which the fasting blood glucose was determined Bioassays: Morinda lucida extract induces endothelium-dependent and -independent relaxation of rat aorta. The solvent fraction in test tubes A and B were moistened with 5 mL of water, while that in test tube C was left dry. The project work was limited only to isolating and detecting of alkaloidal content of Morinda lucida a medicinal plant using solvent because of high cost of spectroscopic instrument like UV, IR and NMR as these would have help in further analysis of the extracted alkaloid. The effects of the four plant extracts were similar on egg hatching and were dose dependent.
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Medicinal plants contain many useful substances some of which luclda biologically active and are known as secondary metabolites. Pharmacologia Volume 4 5: Sixty mice were assigned into six groups. Supplementation with aqueous leaf extract of Morinda lucida enhances immunorestoration and upregulates the expression of cytokines and immunostimulatory markers. Simplice, Tchadjobo Tchacondo, Denise P.
Thus, they can be used in the treatment of infectious morunda caused by these resistant microbes. To 2 mL of the cold water extract in different tubes, was added 6 drops of different alkaloids reagents, namely: Aim Of The Study: Blue-black presence indicated the presence of tannins.
The method used for the column chromatography was according to that described in the works of Matthews, morlnda The rats were housed in polypropylene cages and handled in accordance with international principles guiding the Use and Handling of experimental animals Method of visualization used was anisaldehyde- sulphuric acid spray. In principle revew could be classified either by the biological systems in which they occur or by their chemical structure.
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The baseline fasting blood glucose was first determined before alloxan treatment. Oral treatment of normal rats with MLE fractions: In vitro cytotoxicity studies of 20 plants used in Nigerian antimalarial ethnomedicine.
The important role of histone deacetylases HDACs in the development of cancer has been demonstrated by various studies. The filtrates were used for testing the presence of alkaloids in Morinda lucida.
ML 1molucidin 2and ML-F52 3which are responsible for anti-trypanosomal and anti-leishmanial activities of Morinda lucida Bentham leaves. J Ethnopharmacol Dec 15; 3: To investigate the effect of Morinda lucida Benth Rubiaceae on the reproductive activity of male albino rats.
Herborists were interviewed using a validated questionnaire and species of plants were identified using a combination of field photo guides, local names and voucher specimens.
Alcoholic extracts of four tropical plants Zanthoxylum zanthoxyloides, Newbouldia laevis, Morinda lucida and Carica papaya were screened in vitro for potential anti-parasitic effects against eggs, infective larvae and adult Haemonchus contortus.
The Soxhlet extractive was filtered using a piece of white cotton cloth and the filtrate obtained was completely dried into an aromatic green-brown solid residue over a water-bath. This study evaluated the responses of some antioxidant parameters in selected tissues of Plasmodium berghei-infected mice treated with cysteine-stabilized peptide fraction CSPF of aqueous extract of Morinda lucida leaf.
A control experiment was set up the same way, however instead of the extract; sterile water was each introduced into the hole bored. J Pharm Biomed Anal Feb 29; It separated into two layers with the organic layer below the aqueous layer.
Two and a half liters of absolute ethanol was then added to the morinxa of the powdered sample to cold macerate. One way to prevent resistance is by using new compounds that are not based on existing synthetic antimicrobial agents. This project work is aimed at isolating of alkaloidal content of Morinda lucida a medicinal plant and detecting it with some diodal. Parasitol Res May; 5: Diabetes prevention and control: Differences such as this may be attributed to, the chronological age of the plant, percentage humidity of the harvested material, situation and time of harvest, and whether the method of extraction was a possible source of variation for the chemical composition, toxicity and bioactivity of the extracts Felix,